Top physicist Rong Yu died in a car accident while trying to save her young son Ji Shunying. Seventy years later, her soul transmigrates into the body of an unloved eldest miss of the Rong family. Returning to the present world, she bumps into her son, who has become a business tycoon, and gets to know her great-grandsons Ji Zhiyuan and Ji Zhouye. Relying on her extraordinary IQ and cross-generational life experience, Rong Yu crushes her biased stepmother's family and campus rivals, scores high on a talent show, sweeps physics and math competitions, and gradually reveals her identity. After waking up, Ji Shunying recognizes his mother, and the whole family venerates her as their great-grandmother. She reorganizes the Ji Group, pierces through the scheming secretary Lan Rouxue's calculations, disciplines rebellious younger generations, and guards her descendants and concludes her seventy-year regrets with the dual identity of an elder and a scientific research powerhouse.