Ancient physician Su Yunhe's soul transmigrates to the modern era, becoming Su family's legitimate daughter framed and kept under house arrest by her stepmother Liu Meilan. To break free from her predicament, she enters into a contract marriage with Lu family head Lu Sinian, who is tormented by old injuries from a car accident. Su Yunhe opens a traditional Chinese medicine studio, making a name for herself with superb medical skills while step by step gathering evidence to investigate the truth behind her mother's murder. She confronts her stepmother, stepsister, and the ambitious Lu Ziheng, breaks through multiple plots of poisoning and framing, and gathers human and physical evidence to topple all villains. The two tear up their agreement, guard each other with true love, pass down ancient traditional Chinese medicine, and complete their revenge and self-realization.