A modern divine physician, Su Ruojin, transmigrates to become the adopted daughter of the prefect's manor, only to be expelled by the Lin family. Relying on her dual mastery of medicine and poisons, she opens the Ren'ai Hall. Repeatedly exposing the misdeeds of the quack doctor Cai Fanzhou and the fake daughter Lin Wanqing, she fortuitously saves the little prince Xiaobao who suffers from autism and a dull illness. She wins the devoted protection of the Prince Regent Xiao Yanchu, who goes by the alias Jiang Qi'an. Along the way, she retrieves her Su family relatives, opposes villains such as Empress Dowager Wei, practices medicine to save the world, donates precious medicinal herbs for disaster relief, resolves various troubles from the Zhao and Cai families, gradually cures Xiaobao, harbors mutual affection with Xiao Yanchu, establishes herself through medicine all the way, and gathers the companionship of family and friends.