A meteorite is about to strike the Earth, and working stiff Shen Zhiyi unexpectedly inherits an abandoned zoo left by her grandfather. She unlocks a group of mutant animals in the hibernation pods, accompanied by partners such as a fire-breathing Northeast tiger and a high-IQ parrot. When the doomsday virus breaks out, she leads a mutant beast squad to venture out and find scattered animal companions, struggling to survive in the perilous doomsday while searching for her out-of-contact parents.