Cen Qingyuan is reborn back to the day her husband Gu Jingyao took his mistress Wen Manrou south. No longer bitterly loving and pleading to make him stay, she tears up the marriage agreement on the spot, hands over the pharmacy, and relies on her medical skills to set up independently, opening Cen's Medicinal Cuisine. After taking over the pharmacy, Gu Jingyao is eager for quick success and instant benefits, cutting corners and using moldy medicinal herbs to make medicine, which ultimately brews a medical disaster, ruining the family business and leaving him deserted by all. Their children realize their mistake and run to Cen Qingyuan, while Gu Jingyao repents thoroughly and kneels to beg for reconciliation, only to be flatly rejected by her. In the end, Cen Qingyuan uses her exquisite medical skills to make Cen's big, relying on herself to carve out an open and secure life.