Miao medicine successor Su Niannian returns to the Su family to acknowledge her relatives, using her extraordinary ability to distinguish fragrance and medicine to see through the bad luck, poison schemes, and fortune-seizing conspiracy in the mansion, and investigates the truth about her grandfather's death. She and Lu Sihan, who is lurking for revenge, go from probing each other to standing side by side in mutual trust, fighting against Shen Chang'an, who covets the Guiyuan incense formula, and the traitor in the Su family amidst heavy fog, uncovering the death of Fu Bo, Lu Sihan's identity, and the dark secrets of illegal drug research. After going through betrayal, hunting, and choices, the two hold fast to their benevolent medical hearts, reopen the medical clinic to save people, and also reap a lifelong companion love.