A global blue fog catastrophe sweeps across the world, and 90 percent of humans mutate into bloodthirsty and manic fog-corroded beings. Cities are reduced to ruins, and order completely collapses. Lin Chen, an ordinary person, manages to survive in the doomsday desperate situation, knowing the survival rules thoroughly, being meticulous in mind, and being decisive in killing. During a material searching trip, he accidentally rescues Su Wan, a high-value medical department talented woman trapped in a desperate situation. Gentle, resilient, intelligent, and courageous, Su Wan becomes the only light in Lin Chen's doomsday. One is good at combat and survival, and the other is proficient in medical first aid. The two support each other and fight side by side in the wasteland world full of crises, scarce resources, and distorted human nature.