Wrongly destroying the engagement, Prince Jing regrets it at the time of reunion. Legitimate daughter Su Ziyu is framed by concubine-born sister Su Lingwei, her engagement is destroyed, and she is imprisoned in a utility room on the verge of death where she awakens medical skills. Cousin Shen Yanci helps her clear her suspicion. Thereafter, Su Ziyu reveals her medical skills, saving an elderly man suffering from palpitations on the street, rescuing a drowning daughter at a palace banquet, and after a conflict with the second miss is rumored against by Lady Liu, she is selected by the imperial family and dispatched to Jiangnan to fight an epidemic. On the way, she accidentally encounters the injured Prince Jing Xiao Jingyuan. After several experiences, Xiao Jingyuan finally understands Su Ziyu, feeling deep regret for the initial breakup of the engagement.