Chen Pi travels back in time to the 1980s and unexpectedly binds himself to the Medicine God System. Simply by coming into contact with patients, he can unlock various medical and pharmaceutical formulas. Settling down at a rural clinic, he uses the medical knowledge granted by the system to overcome one challenging illness after another, saving ordinary people suffering from various ailments. Along the way, he faces misunderstanding and skepticism from those around him, but remains true to his calling as a doctor. By a twist of fate, he meets Zhao Lingxian, a woman from a family of traditional Chinese medicine practitioners. Together, they work to put medical formulas into practice and make affordable, effective medicines accessible to more people. Through each consultation and treatment, Chen Pi discovers the true value of his new life after traveling through time.