Han Wangshu, the direct successor of the Supreme Physician, was framed by Han Qinglin of the main Han family branch, resulting in his meridians being sealed and reducing him to an accountant at Jishitang. Biding his time for three years, he studied the principles of medicinal properties and mutual antagonism using ordinary herbs and plants. At the Grand Imperial Medicine Appraisal Ceremony, using commonplace items such as dried fruits and calming herbs, he exposed the tampered imperial medicine formula and uncovered the wrongful theft of the formula. Indifferent to power and authority, he rejected high positions and embarked on the path of seeking the lost heritage of the Supreme Physician, using the righteous path of pharmacology to heal the world and save people.