Wealthy heiress Lin Qingxue jumped into the river rather than accept a family-arranged marriage, and was rescued by Chen Feng, the divine doctor of Qingshan who had just come down the mountain. Concerned about her reputation, Lin Qingxue demanded that Chen Feng take responsibility for her, and the two obtained their marriage certificate. Upon returning to the Lin family, Chen Feng faced mockery on all sides, yet he used his superb medical skills to save the matriarch, stunning everyone. When the Gu family pressured and forced a divorce, Chen Feng mobilized his master's connections to neutralize the crisis. Lin Qingxue's Mysterious Ice Spirit Constitution attracted the covetous eyes of the Ghost Medical Sect, drawing everyone into a twenty-year-old mystery. Side by side, Chen Feng and Lin Qingxue braved adventures together, explored the Medicine King's Tomb, uncovered the truth behind his mother's disappearance and the Mysterious Ice Spirit Constitution, and jointly thwarted the conspiracy of the Ghost Medical Sect.