Amidst the chaotic era of warlord fragmentation, Su Zhi from a traditional Chinese medicine family is forced into a proxy marriage to ward off bad luck with the critically injured and dying Warlord Lu Jingyuan. Relying on her miraculous medical skills, she saves her husband, and with wisdom and resilience, she defeats the repeated provocations of her love rival, breaking free from the exploitation and scheming of her original family. When a plague sweeps through, she rushes to the affected area regardless of life or death to practice medicine and save the world. Having gone through life-and-death storms, the two rush toward each other in the troubled times.