When ordinary young man Jiang Ning goes to meet his online girlfriend, Liu Ruyan, she mysteriously disappears. As he investigates, he discovers that every member of his family possesses unique supernatural abilities, while he himself has mastered traditional Chinese medicine passed down through his ancestors. To rescue his beloved, Jiang Ning joins forces with his companions, traveling far and wide, venturing into secret realms, fighting unlawful forces, and exposing conspiracy after conspiracy. After overcoming countless trials, they find the source of spiritual energy and resolve the crisis. In the end, they establish a new home, bring the conflicts of the past to a definitive close, and live together in peace and happiness.