The lucky little princess Zhu Zhu is born into Prince Duan's household, where she is cherished and accompanied by her elder brother Sheng Minglin, the Fourth Prince, the Seventh Prince, and others. The young genius physician Huo Chenzhao enters the prince's residence to treat the Seventh Prince and assist everyone in the household. An old case from years ago resurfaces, prompting everyone to secretly investigate the clues and consult two masters to discern the secrets of their fates. Prince Duan travels to Zhongzhou to treat the common people, while Zhu Zhu studies and learns to write under her family's protection. The siblings support one another, and the entire household stands united to face every challenge as their peaceful days continue.