Emergency doctor Chu Nuonuo accidentally becomes the three-and-a-half-year-old legitimate daughter of the Yong'an Marquis Mansion. With her stepmother controlling the inner courtyard and left isolated in the mansion, she has no choice but to seek refuge with her eldest uncle, Chu Xiao, who lives in seclusion in a abandoned courtyard. The former God of War now suffers from leg injuries and cold poison, and the uncle-niece duo decide to support each other: Nuonuo uses her medical skills to see through the abnormal medication use in the mansion and find a way to heal Chu Xiao's injuries; Chu Xiao has her back and helps her reclaim her mother's dowry. As the secrets of the mansion gradually come to light, they must also jointly face the step-by-step coercion of the Eastern Depot and the imperial court. Nuonuo must survive here and help her eldest uncle stand up again.