When the doomsday arrives, Lin Ran is unfortunately bitten by a zombie, becoming a half-zombie who can still maintain her sanity. Relying on her daughter Tangtang's kisses and love to suppress the virus, she takes Tangtang and the golden retriever Mantou on the run to find her husband Chen Mo. They evade zombies and must also guard against Bai Ruolin and others in the survivor camp who covet the natural antibodies in Tangtang's body. After enduring capture, separation, and a life-and-death game, the family is finally reunited and successfully develops the antidote. After the catastrophe, they welcome a brand-new life above the ruins.