Su Qingwan catches her husband, Jiang Beichen, in bed with his mistress, only to see him take the other woman's side. When their daughter is fighting for her life due to leukemia, he abandons her. Su Zhenjiang, Qingwan's biological father, offers a huge reward for bone marrow to save his granddaughter. Unaware of the truth, Jiang Beichen gets on the operating table to curry favor with the powerful, only to discover that the housewife he despised is now someone far beyond his reach.