Jiang Wan, a 21st-century heir to the art of witch medicine, is transported to another world after a car accident and becomes the neglected legitimate daughter of the Duke of Rong's household. Her original counterpart was schemed against and killed by a concubine, but Jiang Wan returns with a portable laboratory space. Facing a biased father, a hypocritical grandmother, and a vicious half-sister, Jiang Wan fights back at every turn with her exceptional medical skills. She saves Consort Jing, who has been poisoned and left seemingly dead, and meets the Sixth Prince, Cheng Yuan. As she investigates the old case surrounding her mother's murder, her spectacular coming-of-age ceremony leaves everyone astonished. Amid the undercurrents within the Duke's household, she sets out to reclaim justice for both herself and the original Jiang Wan.