The young girl A Yuan, because she repeatedly let go of the wild animals captured by her stepfather Zhao Kui, was miserably bitten by his poisonous snake and kicked into the rapid river. At the critical moment of life and death, the spiritual eagle that A Yuan had treated three years ago appeared, risking its life to save her ashore and snatch her back from the wolf pack. The eagle spared no effort, being wounded while carrying herbs in its beak to feed her, and A Yuan miraculously survived, recognizing that her life-saving savior eagle was indeed her old friend from back then. A Yuan hugged the exhausted and fallen spiritual eagle and cried bitterly. This miraculous bond where all things have spirits officially opened the legendary prelude of her counterattacking from a desperate situation to become a generation of Medicine King.