A modern master of poison medicine travels through time, becoming the bullied legitimate daughter of the prime minister's estate, Su Shijin. The original owner was persecuted by her younger sister Su Luoyue and Crown Prince Chu Muchen, and forced to jump off a cliff. Su Shijin escapes death and rescues Chu Junche, the Prince Li of War, who is suffering from Gu poison. Armed with medical skills and a portable spatial dimension, she tears apart hypocritical family affections, decisively breaks off the engagement, and exposes Su Luoyue's disguise. The two encounter dangers while searching for medicine, mistakenly enter the sinful Qixiang Village, join hands to rescue oppressed women, and grow mutual affection through life and death. Su Shijin's body gradually recovers and undergoes a transformation, and upon returning to the capital, she encounters a new crisis when her maid Dong'er is kidnapped, facing a new round of dangerous scheming.