After graduating from university and immediately becoming unemployed, Youyou returns to her hometown and opens a shop called the Worry Relief Shop. Unexpectedly, she becomes the owner of a passageway connecting the human world and the supernatural realm. Little monsters, including a baby zombie, a nine-tailed fox, a little skeleton, and a little lamb, come to her seeking help. Using her unconventional tricks, she solves their troubles and gradually forms family-like bonds with them. But just as everything seems to be going well, a crisis is approaching.