A modern wildlife biologist, Shen Qingyi, time-travels and is reduced to an exiled orphan of the convicted Shen family. To secure a foothold, she chooses to marry Gu Han, a down-and-out swordsman suffering from strange poisons and framed by others. Shen Qingyi awakens the special ability to understand all living creatures, relying on her skills in gathering herbs and identifying poisons to survive in the Valley of Ten Thousand Beasts. Together with her younger brother Chu Lan, the two resist local evil forces and the conspiracy of the Duke of Ning from the capital, collect evidence of the miscarriage of justice, and rely on wisdom, medical skills, and the help of others to break through heavy crises, wash away her family's grievance of blood, protect those around her, and welcome a brand-new life.