The youth Shen Yan was fostered in the Linchuan Pharmacy since childhood, appearing merely as an ordinary apothecary apprentice, yet harboring the Zhushan Sect's inherited supreme treasure, the "Dragon Spine", within his body. His master, Gu Sanqiu, burned away his life to protect the secret, and Shen Yan embarked on the path of finding the truth. After returning to the Zhushan Sect, he gradually uncovers the mysteries of sect leaks, bone sealing, and the Yanmo Valley's bone-seizing conspiracy. Amidst trust and betrayal, protection and revenge, Shen Yan endures hardships, growing from a youth reliant on others' protection into the Lord of Rebellious Bones who bears his destiny alone.