Modern medical and poison PhD Lin Zixi crosses over and is reborn, possessing the body of the prime minister estate's legitimate daughter who was framed and killed by her concubine-born sister and the crown prince. Armed with advanced medical skills and a hundred-treasure space, she returns aggressively to ruthlessly tear apart her concubine-born sister Lin Jingwan and biased father Lin Jinzhi who framed her, slap the heartless crown prince Mo Yunqian, and embark on a path of revenge and counterattack. The cold-faced War Prince Mo Yunli had deep affection for her in their past life, and this lifetime they run towards each other in a two-way devotion. Together, they pacify the poison plague in Chuicheng, outwit enemy state ministers, and crack court succession conspiracies. The female lead also helps her mother escape an unfortunate marriage, opens a medical clinic to accumulate power, and finally has a blissful grand wedding with Mo Yunli, living out a fiercely satisfying life amidst power struggles.