Orphan A Wu once received kindness from Shen Wanqing, the legitimate daughter of the Marquis's estate. Shen Wanqing was plotted against by her family elders and concubine-born sister, falling into dire straits. A Wu learned toxic medical arts and, using a fake face to transform into Shen Wanqing, returned to the Marquis's estate, being forced to marry the disabled Prince Xiao Heng. The two tested each other and joined hands to deal with various plots. Amidst the crisis, Xiao Heng discovered her secret and quietly protected her. After the storm subsided, A Wu removed her disguise and confessed her true identity. Xiao Heng did not care about her appearance, and the two resolved their inner barriers, traveling together across rivers and mountains to practice medicine and save the world.