The female physician Shen Jichu establishes Jichutang in Yancheng. With her extraordinary medical skills, she saves the Loyal and Brave Marquis and later risks her life sneaking into the capital to rescue her younger brother, Shen Jingzhe, who has been framed. After returning home, she continues practicing medicine and helping those in need. When a mountain collapses and disaster strikes, she rushes to the affected area to save lives and heal the injured, winning the admiration of the chief physician of the Imperial Medical Academy through her medical expertise and compassionate heart. To find a cure for her beloved daughter's mysterious and difficult illness, she embarks on a journey beyond the frontier. Along the way, Shen Jichu compassionately rescues people who have been abducted and helps struggling grassland tribes. Although danger lurks at every turn, she remains true to her calling as a physician, holding fast to kindness and protecting her family and the vulnerable in desperate circumstances, bringing warmth and hope to the vast wilderness.