In her previous life, Shen Jinghong was a disgraced concubine confined to the Cold Palace, where the Empress had her killed with a cup of poisoned wine. Reborn, she awakens on the third day after being banished to the Cold Palace. The poisoned wine is already on its way, and her maid, Bi Luo, is hanging by a thread. Armed with memories of her previous life and extraordinary mastery of silver needles, she saves lives and neutralizes poisons, carefully plotting every move. The Empress repeatedly sends people to assassinate her, but Shen Jinghong defeats every scheme with her medical skills and strategic brilliance. At the Empress Dowager's birthday banquet, she publicly exposes the Empress's poisoning plot. In a secret passage beneath the Cold Palace, she discovers her birth mother's belongings and learns that she is the sole surviving descendant of the Mu family, which was massacred. Meanwhile, the Heavenly Secrets Pavilion arrives with a token to acknowledge its rightful master and restore her position. When the Empress and Chancellor Zhu launch a palace coup, Shen Jinghong neutralizes their forces with a bone-weakening powder.