The Shen family is suddenly framed and sentenced to execution in its entirety. Seventeen-year-old Shen Zhirou falls into the hands of Marquis Shen Yan, who intends to present her to the Crown Prince. However, she is ambushed by the Marchioness and dies tragically in a brothel. Shen Zhiwei, suffering from poisonous skin rashes and concealing her appearance behind a veil, is reduced to a servant of the Imperial Music Bureau. Enduring humiliation to survive, she secretly studies medicine. She sets her sights on Shen Yan's younger sister, who suffers from a heart condition, and carefully engineers a chance encounter. Using the opportunity to treat her illness, she enters the Marquis's residence and proceeds cautiously with every step. Turning her medical skills into a weapon, she seeks to reclaim the blood debt from all her enemies and uncover the truth behind the wrongful case that destroyed her family.