Broke young man Chen Chang'an, in order to raise medical fees for his mother, sells an ancestral antique painting, accidentally activating the painting with blood to break into a secret realm. He acquires the fivefold immortal inheritance of immortal martial arts, medical dao, strange arts, celestial tones, and ingenious craftsmanship, and even gains guidance from an immortal ox. Relying on his heaven-defying abilities, he wanders the streets, saves female CEO Qin Rou, treats dignitaries, appraises antiques, settles grudges, opens a divine shop, joins the martial arts alliance, and slaps the faces of all sorts of petty people all the way. Rising against the current from a bottom-layer poor boy, he stirs up winds and clouds in Yuncheng, forging a legend of a grassroots counterattack.