After ten years of working in the mines, Chen Ye develops severe pneumoconiosis. With nowhere else to turn, he seeks help from his younger brother, Chen Hao, whom he had supported through years of frugal living and tremendous sacrifice until he became a chief physician. Unexpectedly, Chen Ye is publicly humiliated by his own brother and his snobbish sister-in-law, Lin Jiao. In despair, he retreats alone into the remote mountains, where he accidentally awakens the ancestral Manual of Mountain Roaming. He masters extraordinary skills in reading mountains and identifying medicinal herbs, setting traps and controlling beasts, avoiding dangers, and surviving in the wilderness. Venturing alone into the vast hundred thousand mountains, he gathers countless rare and priceless treasures. After returning to civilization, he successively defeats local bullies, the Jiangcheng Wu family that monopolizes the market, local enterprises profiting from destroying forests, and foreign financial conglomerates seeking to plunder China's medicinal herb resources.