Shen Qiyue was abandoned by the crown prince, then turned around to obey an imperial edict for a blessing marriage, wedding the notoriously mad and poisoned Prince Jing, Xie Jinghan. Armed with supreme medical skills, she steadied Prince Jing's poison flare-up with three needles, tearing apart her scumbag father and stepmother, and slapping the green-tea stepsister in the face. When the crown prince plotted rebellion, poisoning the military camp and seizing the throne through a palace coup, she refined medicine to save seven thousand soldiers, rushed into the palace to protect the sovereign and quell the rebellion, helping Prince Jing settle the universe with a single arrow. From a grievance-laden pair brought together for a blessing to mutual lifelong favorites, they ultimately achieved a fulfilling tale of a devoted couple for a lifetime under a prosperous era.