The widow Zhou Xiulan, who suffered endless oppression in her past life, died a miserable death with unresolved grievances. She is reborn back to 1980 and accidentally unlocks her ancestral portable medicine field spanning ten thousand mu. Relying on miraculous medicinal herbs to cure illnesses, save lives, and open a pharmacy, she holds the ledger to settle the blood debts of her black-hearted, vicious relatives. Step by step, she builds her business and gets rich, fiercely transforming from a bringer of bad luck into a universally revered female shopkeeper, thoroughly demanding justice and earning a fortune of ten thousand strings of cash.